Powered by nano-liposomal retinol and centella-derived PDRN, this advanced cream helps reduce the appearance of fine lines, wrinkles, and enlarged pores. MARY & MAY Spicule Retinol PDRN Cream uses advanced spicule micro-needle technology to enhance delivery of powerful anti-aging ingredients. Nano liposome retinol and CICA-PDRN work together to improve wrinkles, minimize enlarged pores, and refine skin texture. Boosted with ceramides, hyaluronic acid, panthenol, niacinamide and allantoin to support the skin barrier and soothe irritation. Suitable for all skin types and gentle enough for sensitive skin when acclimatised and used as directed.